Signals

You can view all signals Lareb has published in the quarterly reports to the Medicines Evaluation Board. You can dowload the signals. Some of these articles are written in Dutch only. Please use the 'search function' for easy access to these signals.  
 

#	Title	Download
1	Adalimumab and neuroendocrine carcinoma of the skin
2	Parenteral medroxyprogesteron and injection site necrosis and atrophy
3	Lenalidomide and psoriasis
4	Escitalopram and headache
5	Aripiprazole and hypothyroidism
6	latanoprost containing products and smell disorders
7	Dutasteride and testicular pain
8	tamsulosin and depressive reactions
9	(es) omeprazole and vitamin B12 deficiency
10	Aripiprazole and aggravated psychosis
11	Pandemic influenza vaccine (Pandemrix®) and narcolepsy
12	An overview of reports on agomelatine
13	desloratadine and increased appetite
14	Angiotensin II Receptor Antagonists and Taste Disorders
15	Sitagliptin and dyspnoea
16	Tamsulonsin and visual disturbances
17	Lacosamide overview
18	Azathioprine and chromaturia
19	Oxaliplatin and laryngospasm
20	Sitagliptine overview
21	Fluorochinolones and stomatitis
22	Ibuprofen and Stevens-Johnson syndrome
23	Duloxetine and shock-like paraesthesia
24	Methylphenidate and erectile dysfunction
25	Ropinirol and nasal congestion
26	Overview of the reports on Cervarix
27	Azathioprine and photosensitivity reactions
28	Bisphosphonates and depression
29	Pandemrix and injection site discolouration
30	Methotrexate and device problems
31	Reports associated with vaccination against influenza A (H1N1)
32	Folic acid and anaphylactic reactions
33	Mirena and ectopic pregnancy
34	ACE-inhibitors and flushing
35	ACE-inhibitors and nightmares or abnormal dreaming
36	Angiotensine II AT1 receptor antagonists and nightmares or abnormal dreaming
37	Serotonin Re-uptake Inhibitors (SSRIs) and shock-like paraesthasias: an update
38	Alpha-1 blocking agents and liver disorders
39	Fexofenadine and bradycardia
40	Angioedema and allergic reactions in metoclopramide containing products
41	Valproic acid and gingivitis
42	Doxycycline and smell and taste disorders
43	Oseltamivir and coumarin potentiation
44	Adalimumab and pustular psoriasis
45	SSRI's and hot flushing
46	Vitamin B12 (cyanocobalamin) and dermatitis acneiform
47	Terbinafine and deafness
48	Fluticasone and epistaxis
49	Norfloxacine and hypoglycaemia
50	Clindamycin and dysgeusia
51	Atomoxetine, Methylphenidate and ejaculation disorder
52	HMG-CoA-reductase inhibitors and tendonitis
53	Itraconazole and dyspnoea
54	Lithium and downbeat nystagmus
55	Clonidine and weight gain
56	Amlodipine en fotosensitiviteit
57	Cisplatin and cerebral infarction
58	Oral iron salts and skin reactions
59	Serotonin Re-uptake Inhibitors (SSRIs) and alopecia
60	Bisphosphonates and alopecia
61	Hypothermia and antipsychotic drugs
62	Bupropion and cardiac ischaemia
63	Tamsulosin and hyperglycemia in patients with type 2 diabetes
64	Omeprazole, esomeprazole and hypomagnesaemia
65	Proton pump inhibitors and tongue discoloration
66	Domperidone and convulsions
67	Salbutamol inhalation and dental caries
68	Phosphodiesterase 5 inhibitors and pulmonary embolism
69	Bisphosponates and stomatitis
70	Valproic acid and curling hair
71	SSRIs and Hypoglycaemia
72	Atomoxetine and tics
73	Tamoxifen and hirsutism
74	Influenza like symptoms after vaginal application of estriol
75	Fluorescein and anaphylactic reactions
76	Risperidon and pipamperon in association with epistaxis
77	Itraconazole and pancreatitis
78	Angiotensin-II receptor antagonists and paraesthesia
79	Topical imidazole derivates and drug interactions
80	Fluconazol en fixed drug eruptions
81	Tamsulosin and epistaxis
82	Overview on pioglitazone
83	Inhaled fluticason and haematoma
84	HMG-CoA-reductase inhibitors and nightmares or abnormal dreaming
85	Loratadine, desloratadine and convulsions
86	tramadol and hot flushes
87	Paroxetine and restless legs
88	HMG coA reductase inhibitors and pulmonary fibrosis
89	Omeprazole and coumarine interactions
90	SSRIs and aggression
91	Anti-epileptic drugs and suicidal behaviour
92	Mirtazapine en droge mond
93	Lithium intoxication associated with simultaneous use of trimethoprim
94	Cefepime en neuropsychiatric symptoms
95	Zyban® en ballisme
96	Hyperpigmentatie tijdens het gebruik van SSRI’s
97	Risperdal® en gestoorde glucose tolerantie
98	Neonatale intracraniële bloeding geassocieerd met gebruik van paroxetine tijdens de zwangerschap
99	Stocrin en leverfalen
100	Cosopt® oogdruppels en sinusitis
101	Pergolide en effect op libido
102	Miconazol en ontregeling van antistolling
103	Latanoprost-oogdruppels en hoofdpijn
104	Amoxiciline-clavulaanzuur (Augmentin®) en leverfunctiestoornissen
105	Mirtazapine en myalgie
106	Claritromycine en psychotische verschijnselen
107	Rofecoxib en cardiale bijwerkingen
108	Pergolide en fibrosering
109	Clopidogrel en trombotische trombocytopenische purpura
110	SSRI’s en galactorroe
111	Minocycline en interstitiële pneumonie
112	Lamotrigine en ernstige huidreacties
113	Toxisch anticholinerg delier bij gelijktijdig gebruik van tolterodine en fluconazol
114	Simvastatine en eczeem
115	Loperamide en urineretentie
116	Overview of cardiac adverse drug reactions reported in association with rosiglitazone
117	Imiquimod and severe skin disorders
118	Lamictal (lamotrigine) en alopecia
119	Tramadol and hiccups
120	Cetirizine, levocetirizine and arthralgia
121	Pantoprazole and taste disorders
122	Venlafaxine and sexual disinhibition
123	Valproic acid and pubertas praecox
124	Methylphenidate and hyperhidrosis
125	Latanoprost and dizziness
126	Omeprazole and erectyle dysfunction
127	Nilutamide and chromotopsia
128	Montelukast and depressive symptoms
129	Citalopram and priapism
130	valproic acid is association with hyponatremia and SIADH
131	Topical tacrolimus and malignancies
132	Gosereline and psychiatric disorders in the treatment of prostate cancer
133	Low dose carbasalate calcium and tinnitus
134	SSRIs and venlafaxine in association with bruxism
135	Olanzapine and amenorrhea
136	Fluticasone inhalation and behavioual changes in children
137	Bupropion and suicidality
138	Ace-inhibitors and hallucinations
139	Tamsulosin antagonists and anginal complaints
140	Sevoflurane and ventricular tachycardia
141	Quetiapine and extrapyramidal effects
142	Olanzapine and hyponatraemia
143	AT1-receptor antagonists and psoriasis
144	Vitamin B12 induced acneiform dermatitis
145	SSRIs and tinnitus
146	Losartan and psychiatric adverse drug reaction
147	Itraconazole and erectile dysfunction
148	Quetiapine and micturation disorders
149	Proton-pump inhibitors and gynecomastia
150	Pergolide and pathologic gambling
151	Hydroxychloroquine and hearing loss
152	Neuropsychiatric side effects associated with dextromethorphan
153	HMG-CoA-reductase inhibitors and hypersensitivity pulmonary reactions
154	Losartan and taste disorders
155	Bosentan and coagulation disorders
156	A combination of metoclopramide and selective serotonin reuptake inhibitors: additional extrapyramidal effects?
157	Itraconazole and paresthesias
158	Skin reactions associated with the use of oral terbinafine
159	Sodium aurothiomalate and nitritoid reactions: concomitant use of an ACE-inhibitor as a contributing factor
160	Risperidone and epistaxis
161	Infliximab and questionable efficacy of recommendations on tuberculosis screening
162	Clozapine, olanzapine and rhabdomyolysis
163	Cisapride and cardiac arrhythmia: what advice should be given on the frequency of ECG-check?
164	Venlafaxine and extrapyramidal effects
165	HMG-CoA-reductase inhibitors and lichenoid eruption
166	HMG-CoA-reductase inhibitors and taste disorders
167	Anaphylactic reactions on the combination of paracetamol, propyphenazone and caffeine (Saridon®)
168	Desmopressin and psychiatric effects
169	Tramadol and hallucinations
170	Anaphylactic reaction on sulphur hexafluoride
171	HMG-CoA-reductase inhibitors and neuropathy
172	Overview of rosuvastatin reports
173	Lanreotide and loss of scalp hair
174	Infections can increase clozapine levels, resulting in delirium: an update
175	Venlafaxine and hypertension
176	Terbinafine and lupus erythematosus
177	Haloperidol and visual disturbances
178	Sumatriptan and zolmitriptan and emotional disinhibition
179	Severe skin reactions in patients receiving cranial radiotherapy while using phenytoin.
180	Naphazoline and mydriasis
181	Hydroquinine hydrobromide and visual disturbances
182	Overview of anakinra reports
183	Venlafaxine and severe respiratory disorders
184	Thyrax Duotab 0,025 mg® and allergic reaction
185	Concurrent use of verapamil or diltiazem and HMG-CoA reductase inhibitors increases the risk of muscle related ADRs
186	SSRIs and weight gain
187	An overview of reports concerning implantation complications and unintended pregnancy on etonogestrel
188	Gabapentin and various sexual disorders
189	Selective serotonergic vasoconstrictors in suspected association with pain activation
190	An overview of reports on sirolimus
191	Sibutramine and manic psychosis
192	Nadroparin-induced calcinosis cutis in renal transplant recipients
193	Cardiac failure and dyspnoea associated with the use of itraconazole
194	Stomatitis associated with the use of terbinafine
195	SSRI’s en nauwe kamerhoek glaucoom
196	Alendronate sodium and uveitis
197	Acetylcysteine and diarrhoea
198	Tramadol and myoclonus
199	Sulfasalazine-induced taste disorders
200	Mirtazapine SolTab and mouth paraesthesia / anaesthesia
201	An overview of reports on tiotropium bromide
202	Increased use of metformin and lactic acidosis
203	Infliximab and listeria monocytogenes meningitis
204	Fluconazole and fixed drug eruption
205	Doxycycline and (photo-)onycholysis
206	Cyproterone acetate and osteoporosis
207	HMG-CoA-reductase inhibitors and decreased libido
208	Macrolide antibiotics and myasthenia
209	Bronchiectasis in children in association with mycophenolate mofetil
210	An overview of reports on montelukast
211	GnRH agonists leuprorelin, buserelin or triptorelin and epiphysiolysis
212	Serotonin Re-uptake Inhibitors (SSRI’s) and shocklike paraesthesia
213	Anaphylactic shock associated with technetium (99mTc)-labelled albumin macroaggregates