News updates

New causality assessment method for ADRs on drugs and vaccines

Several causality methods are developed from a theoretical perspective. In daily practice, not all information requested by the ...

Monitoring of drug safety during pregnancy

Lareb performed a web-based questionnaire study to gain insight in current international practices in the monitoring of drug use during pregnancy an...

Maximum daily dose of vitamin B6 in dietary supplements has now been legally established in the Netherlands

From October 1st, 2018, dietary supplements may not contain a daily dose of more th...

Mobile applications, a promising new route for reporting

Offering a simplified reporting form through an app shows to be a promising new way to collect Individual Case Safety Reports (ICSRs)....

Reports of muscle complaints with the new cholesterol lowering drugs alirocumab and evolocumab

Lareb received reports of muscle related complaints for the new cholesterol lowering drugs aliro...

Vitamin B6 in health supplements and neuropathy

Vitamin B6 supplements can cause neuropathy. Higher dosage and prolonged use are risk factors for the development of neuropathy, although neuro...

Reports after seasonal influenza vaccination 2017/2018

In the period from October 1st, 2017 until April 1st, 2018, Lareb received 230 spontaneous reports concerning possible adverse events fo...

What to teach future healthcare professionals about pharmacovigilance

Education about the safety and safe use of medicines is important for medical, pharmacy and nursing students. The framewo...

Effect of paternal medication on offspring

It seems unlikely that the use of medication by the expectant father will pose a risk for his unborn child. However, little research has been done s...