News updates

Maximum quantity of vitamin B6 in dietary supplements

It is known that high doses of vitamin B6 can cause nerve damage in hands and feet, complaints mainly consisting of numbness, tingling or...

Over 50 reports of vitamin B6 in (multi) vitamin preparations and neuropathy

It has been known that high doses of vitamin B6 can cause peripheral neuropathy, manifesting itself with numbness,...

Undergraduate Pharmacovigilance Core Curriculum

Health care professionals play a vital role in pharmacovigilance. They are the ones prescribing and dispensing drugs. They are also involved in...

Muscle rupture associated with statin use

Statins are used in the treatment of hyperlipidaemia. They are among the most commonly prescribed drugs worldwide and are usually well tolerated. How...

Mebeverine and a false positive ecstasy instant drug test

Mebeverine (Duspatal) is a antispasmotic drug which is indicated for the symptomatic treatment irritable bowel syndrome. The SmPC of ...

Topical corticosteroids and steroid withdrawal syndrome in atopic eczema

The Netherlands Pharmacovigilance Centre Lareb received 19 reports of steroid withdrawal syndrome in association with ...

Methylphenidate and priapism

Following reports at the Netherlands Pharmacovigilance Centre Lareb, priapism is a possible side effect of methylphenidate. Priapism is an erection without sexual...

Fixed drug eruption and doxycycline

The Netherlands Pharmacovigilance Centre Lareb received 27 reports suspect for FDE and doxycycline. This association is supported by several case-reports i...

New: Side Effect App

The Netherlands Pharmacovigilance Centre Lareb launched a Side Effect App. In addition to reporting side effects you can receive news about side effects. The App is suita...