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News updates

  • 09 OCT
    Dimethyl fumarate and alopecia

    The Netherlands Pharmacovigilance Centre Lareb has received 92 cases about alopecia associated with the use of dimethyl fumarate. Alopecia is not described in the Dutch Summary of Product Characterist...

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  • 18 SEP
    Anastrozole and depressed mood

    The Netherlands Pharmacovigilance Centre Lareb received 14 reports of depressed mood associated with the use of anastrozole (Arimedex®). In the Summary of Product Characteristics of Arimedex®, mood di...

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  • 28 JUL
    Patient organizations can help enable effective communication of adverse drug reactions

    To improve therapeutic decision making, it is crucial that information regarding adverse drug reactions reaches patients. One possible avenue is to collaborate with patient organizations. In a pilot s...

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  • 13 JUL
    Preparation started to monitor the safety and efficacy COVID-19 vaccines

    An European project has been started to prepare for the monitoring of the safety and efficacy of COVID-19 vaccines. This project aims to conduct preparatory research into data sources and methods that...

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  • 05 JUN
    Burden of adverse drugs reactions with biologics

    Infections and musculoskeletal complaints are adverse drug reactions (ADRs) with the highest burden for the patient, while injection site reactions have the lowest burden according to participants in ...

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  • 27 MAR
    Flucloxacillin and oesophageal complaints

    The Netherlands Pharmacovigilance Centre Lareb received 22 reports of oesophageal complaints associated with the use of flucloxacillin. The complaints varied from oesophageal pain, a burning feeling i...

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  • 12 MAR
    Psychiatric adverse drug reactions in the paediatric population

    Psychiatric adverse drug reactions (ADRs) are common in the paediatric population. 15% of ADRs in children reported to the Netherlands Pharmacovigilance Centre Lareb from 2003 to 2016 concern psychiat...

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  • 12 MAR
    Diabetic ketoacidosis with dapagliflozin and carbohydrate-restricted diet

    Dapagliflozin should not be administrated to patients with an increased risk for diabetic ketoacidosis, for example patients who follow a carbohydrate-restricted or ketogenic diet. However, reports fr...

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  • 11 MAR
    Prevent oesophagitis when using dabigatran

    Oesophagitis is a known adverse drug reaction (ADR) of the direct acting oral anticoagulant dabigatran (Pradaxa®). The Netherlands Pharmacovigilance Centre Lareb has received 33 reports of oesophageal...

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  • 04 MAR
    Lamotrigine and photosensitivity

    The Netherlands Pharmacovigilance Centre Lareb received three reports of photosensitivity associated with the use of lamotrigine. Patients experienced an itchy skin rash on the skin that was exposed t...

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